Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | TDO2 | P48775 | 4/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 3/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17871862 | 0.98 | IDO1 (0.41) | IDO1TDO2IDO2S1PR2S1PR4 | |
| SCHEMBL14675546 | 0.86 | IDO1 (0.41) | IDO1TDO2IDO2MAPTTP53 | |
| SCHEMBL23934953 | 0.81 | TACR1 (0.44) | MAPTSMN1; SMN2TACR1LMNAESR1 | |
| Hydrochloric Acid SCHEMBL19665100 | 0.80 | TACR1 (0.43) | MAPTSMN1; SMN2TACR1LMNAESR1 | |
| SCHEMBL22927822 | 0.80 | IDO1 (0.42) | IDO1TDO2IDO2SLC6A4DPP4 | |
| SCHEMBL96016 | 0.80 | S1PR2 (0.38) | IDO1TDO2IDO2S1PR2S1PR4 | |
| SCHEMBL19665163 | 0.79 | IDO1 (0.39) | IDO1TDO2MAPTTACR1LMNA | |
| SCHEMBL95504 | 0.79 | MLKL (0.45) | S1PR2S1PR4S1PR3MAPTLMNA | |
| SCHEMBL27886161 | 0.79 | CHRM1 (0.52) | MAPTTP53SMN1; SMN2LMNAESR1 | |
| SCHEMBL14677950 | 0.78 | TACR1 (0.41) | MAPTSMN1; SMN2TACR1LMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902725-B2 | Heterocyclic derivatives as RORgamma modulators | GENFIT (FR) | 2018-02-27 | — | — | US | disclosed |
| US-20170349582-A1 | HETEROCYCLIC DERIVATIVES AS RORGAMMA MODULATORS | GENFIT (FR) | 2017-12-07 | — | — | US | disclosed |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-9499579-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-9371353-B2 | Oligonucleotide with protected base | AJINOMOTO CO., INC. (JP) | 2016-06-21 | — | — | US | disclosed |
| US-20150080565-A1 | OLIGONUCLEOTIDE WITH PROTECTED BASE | AJINOMOTO CO., INC. (JP) | 2015-03-19 | — | — | US | disclosed |
| US-8846885-B2 | Oligonucleotide with protected base | AJINOMOTO CO., INC. (JP) | 2014-09-30 | — | — | US | disclosed |
| US-8546534-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO. INC. (JP) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349582-A1 | HETEROCYCLIC DERIVATIVES AS RORGAMMA MODULATORS | RORC, RORB, RORA | IDO1 1036/4885TDO2 3421/4885IDO2 1318/4885 |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, BCAT2, IAPP | IDO1 1454/4885TDO2 3091/4885IDO2 1195/4885 |
| US-20150080565-A1 | OLIGONUCLEOTIDE WITH PROTECTED BASE | POLRMT, POLN, RNGTT | IDO1 4236/4885TDO2 2373/4885IDO2 3835/4885 |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, IAPP, BCAT1 | IDO1 742/4885TDO2 3735/4885IDO2 734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.