SCHEMBL23935517

SCHEMBL23935517

COc1cc(CC(N)C(=O)O)ccc1C(=O)NO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 6/20 0.50
LDHA P00338 1/20 0.50
KDM4E B2RXH2 1/20 0.48
USP2 O75604 1/20 0.48
EGFR P00533 1/20 0.48
LCK P06239 1/20 0.48
FYN P06241 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
ALOX15 P16050 1/20 0.48
PTGS1 P23219 1/20 0.48
HTR2A P28223 1/20 0.48
PTGS2 P35354 1/20 0.48
RECQL P46063 1/20 0.48
HIF1A Q16665 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
TPH1 P17752 7/20 0.47
NR1I2 O75469 1/20 0.45
PPARG P37231 1/20 0.45
AGTR2 P50052 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22108677 1.00 SLC7A5 (0.50) SLC7A5LDHAKDM4EUSP2EGFR
SCHEMBL22108691 0.90 SLC7A5 (0.56) SLC7A5LDHAKDM4EUSP2EGFR
SCHEMBL22444859 0.90 SLC7A5 (0.56) SLC7A5LDHAKDM4EUSP2EGFR
SCHEMBL22108591 0.85 ADRB3 (0.50) SLC7A5LDHAKDM4EUSP2EGFR
SCHEMBL28741592 0.85 ADRB3 (0.50) SLC7A5LDHAKDM4EUSP2EGFR
SCHEMBL23935852 0.85 SLC7A5 (0.48) SLC7A5LDHAKDM4EUSP2EGFR
SCHEMBL22108673 0.83 LDHA (0.49) LDHAPPARGHDAC11ALDH1A1HDAC6
SCHEMBL159000 0.82 LDHA (0.73) SLC7A5LDHAKDM4EUSP2EGFR
SCHEMBL159001 0.82 LDHA (0.73) SLC7A5LDHAKDM4EUSP2EGFR
SCHEMBL31242504 0.82 LDHA (0.73) SLC7A5LDHAKDM4EUSP2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3896056-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2021-10-20 EP disclosed