SCHEMBL23936134

SCHEMBL23936134

CC1(C)c2ccccc2-c2cccc(-c3ccc4nc(-c5ccccc5)nc(-c5ccccc5)c4c3)c2C1(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WHR1 P49842 1/20 0.45
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
ATM Q13315 1/20 0.42
KDM4E B2RXH2 6/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.36
PIK3CD O00329 1/20 0.34
PIK3CA P42336 1/20 0.34
PIK3CB P42338 1/20 0.34
MTOR P42345 1/20 0.34
PIK3CG P48736 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PRNP P04156 1/20 0.34
MAT2A P31153 1/20 0.34
TP53 P04637 1/20 0.34
MAPK1 P28482 2/20 0.33
OPRK1 P41145 1/20 0.33
NT5E P21589 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23936132 0.92 WHR1 (0.44) WHR1KMT2AMEN1ATMKDM4E
SCHEMBL23936024 0.88 WHR1 (0.45) WHR1KMT2AMEN1ATMKDM4E
SCHEMBL23936027 0.88 WHR1 (0.47) WHR1KMT2AMEN1ATMKDM4E
SCHEMBL23936470 0.88 WHR1 (0.47) WHR1KMT2AMEN1ATMKDM4E
SCHEMBL23936135 0.84 KDM4E (0.48) KMT2AMEN1ATMKDM4EALDH1A1
SCHEMBL23936707 0.83 MEN1 (0.46) WHR1KMT2AMEN1ATMKDM4E
SCHEMBL23936737 0.82 MEN1 (0.50) WHR1KMT2AMEN1ATMKDM4E
SCHEMBL23935970 0.82 L3MBTL1 (0.40) WHR1KMT2AMEN1ATMKDM4E
SCHEMBL23936421 0.82 MAPT (0.35) KMT2AMEN1ATMKDM4EALDH1A1
SCHEMBL18455542 0.81 WHR1 (0.45) WHR1KMT2AMEN1ATMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed