SCHEMBL23936277

SCHEMBL23936277

c1ccc(-c2nc(-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)nc3ccccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ATM Q13315 1/20 0.50
WHR1 P49842 1/20 0.41
NUDT1 P36639 3/20 0.39
ADORA2A P29274 3/20 0.39
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 3/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 2/20 0.36
LMNA P02545 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PDK1 Q15118 1/20 0.35
ACP1 P24666 1/20 0.35
RAD52 P43351 1/20 0.35
PDK2 Q15119 1/20 0.35
NR1I3 Q14994 2/20 0.34
ACACA Q13085 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23936717 0.93 MEN1 (0.53) MEN1KMT2AATMWHR1NUDT1
SCHEMBL23936297 0.86 MEN1 (0.46) MEN1KMT2AATMWHR1NUDT1
SCHEMBL18418951 0.86 MEN1 (0.54) MEN1KMT2AATMWHR1NUDT1
SCHEMBL19164152 0.85 MEN1 (0.52) MEN1KMT2AATMWHR1NUDT1
SCHEMBL18418955 0.85 MEN1 (0.52) MEN1KMT2AATMWHR1NUDT1
SCHEMBL23935998 0.84 MEN1 (0.44) MEN1KMT2AADORA2AALDH1A1KDM4E
SCHEMBL23936112 0.84 MEN1 (0.51) MEN1KMT2AATMWHR1NUDT1
SCHEMBL23935993 0.83 MEN1 (0.43) MEN1KMT2AATMWHR1NUDT1
SCHEMBL23936477 0.83 MEN1 (0.43) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL23936215 0.83 KMT2A (0.48) MEN1KMT2AATMWHR1NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed