SCHEMBL23936717

SCHEMBL23936717

c1ccc(-c2nc(-c3ccc4c(c3)-c3ccccc3C(c3ccccc3)(c3ccccc3)C4(c3ccccc3)c3ccccc3)nc3ccccc23)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
ATM Q13315 1/20 0.53
WHR1 P49842 1/20 0.41
NUDT1 P36639 3/20 0.39
ADORA2A P29274 3/20 0.39
MAPT P10636 4/20 0.37
GAA P10253 1/20 0.37
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 4/20 0.36
HPGD P15428 2/20 0.36
ABCG2 Q9UNQ0 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PDE5A O76074 1/20 0.35
PDK1 Q15118 1/20 0.35
THRB P10828 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23936297 0.93 MEN1 (0.46) MEN1KMT2AATMWHR1NUDT1
SCHEMBL23936277 0.93 MEN1 (0.50) MEN1KMT2AATMWHR1NUDT1
SCHEMBL23936477 0.91 MEN1 (0.43) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL23936215 0.90 KMT2A (0.48) MEN1KMT2AATMWHR1NUDT1
SCHEMBL23936177 0.89 KMT2A (0.46) MEN1KMT2AATMWHR1MAPT
SCHEMBL21868280 0.86 MEN1 (0.55) MEN1KMT2AATMWHR1NUDT1
SCHEMBL19759977 0.85 MEN1 (0.48) MEN1KMT2AATMWHR1NUDT1
SCHEMBL24647413 0.84 MEN1 (0.52) MEN1KMT2AATMWHR1NUDT1
SCHEMBL19759929 0.84 MEN1 (0.47) MEN1KMT2AATMWHR1NUDT1
SCHEMBL23936199 0.84 MEN1 (0.44) MEN1KMT2AATMADORA2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed