Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.35 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 11/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064195 | 1.00 | HRH3 (0.42) | HRH3HRH2HRH1ALOX15GNAI3 | |
| SCHEMBL14173452 | 0.88 | ALOX15 (0.50) | HRH3ALOX15GNAI3GNAO1GNAI1 | |
| SCHEMBL23936820 | 0.83 | — | — | |
| SCHEMBL13874921 | 0.82 | HRH2 (0.43) | HRH3HRH2HRH1 | |
| SCHEMBL12995614 | 0.82 | HRH2 (0.43) | HRH3HRH2HRH1 | |
| SCHEMBL16380998 | 0.82 | HRH2 (0.43) | HRH3HRH2HRH1 | |
| SCHEMBL27420609 | 0.81 | HRH3 (0.46) | HRH3HRH2HRH1GNAI3GNAO1 | |
| SCHEMBL20618434 | 0.81 | HRH3 (0.46) | HRH3HRH2HRH1GNAI3GNAO1 | |
| SCHEMBL765377 | 0.80 | HRH2 (0.42) | HRH3HRH2HRH1CARM1PRMT6 | |
| SCHEMBL21226644 | 0.78 | HRH2 (0.47) | HRH3HRH2HRH1GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475277-B1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-10-20 | — | — | EP | disclosed |