Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | PRKX | P51817 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2374434 | 0.90 | APP (0.70) | APPMAPTSNCAAKT1CYP19A1 | |
| SCHEMBL2374425 | 0.90 | APP (0.70) | APPMAPTSNCAAKT1CYP19A1 | |
| SCHEMBL2373649 | 0.87 | APP (0.55) | APPMAPTSNCAAKT1CYP19A1 | |
| SCHEMBL23936983 | 0.87 | APP (0.52) | APPMAPTSNCAAKT1CYP19A1 | |
| SCHEMBL2373639 | 0.87 | APP (0.55) | APPMAPTSNCAAKT1CYP19A1 | |
| SCHEMBL23936976 | 0.83 | APP (0.49) | APPMAPTSNCAAKT1CYP19A1 | |
| SCHEMBL15731546 | 0.83 | APP (0.81) | APPMAPTSNCA | |
| SCHEMBL13863145 | 0.83 | APP (0.57) | APPMAPTSNCAAKT1CYP19A1 | |
| SCHEMBL23936987 | 0.80 | APP (0.76) | APPMAPTSNCA | |
| SCHEMBL13863152 | 0.80 | APP (0.47) | APPMAPTSNCAAKT1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345545-B1 | FUNCTIONALIZED MAGNETIC NANOPARTICLES AND USE IN IMAGING AMYLOID DEPOSITS AND NEUROFIBRILLARY TANGLES | UNIV CALIFORNIA (US) | 2021-10-20 | — | — | EP | disclosed |