Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 20/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | SNCA | P37840 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15731546 | 0.96 | APP (0.81) | APPMAPTSNCA | |
| Florbetapir SCHEMBL3356976 | 0.86 | APP (1.00) | APPMAPTSNCA | |
| Florbetapir F 18 SCHEMBL14826096 | 0.86 | APP (1.00) | APPMAPTSNCA | |
| Florbetapir F 18 SCHEMBL3356981 | 0.86 | APP (1.00) | APPMAPTSNCA | |
| Florbetapir SCHEMBL29375540 | 0.86 | APP (1.00) | APPMAPTSNCA | |
| Florbetapir F 18 SCHEMBL29517039 | 0.86 | APP (1.00) | APPMAPTSNCA | |
| SCHEMBL13827059 | 0.85 | APP (0.79) | APPMAPTSNCA | |
| SCHEMBL13328311 | 0.85 | APP (0.79) | APPMAPTSNCA | |
| SCHEMBL13827085 | 0.84 | APP (0.77) | APPMAPTSNCA | |
| SCHEMBL13827030 | 0.84 | APP (0.81) | APPMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345545-B1 | FUNCTIONALIZED MAGNETIC NANOPARTICLES AND USE IN IMAGING AMYLOID DEPOSITS AND NEUROFIBRILLARY TANGLES | UNIV CALIFORNIA (US) | 2021-10-20 | — | — | EP | disclosed |