Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19969174 | 0.92 | CTSS (0.60) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL18057248 | 0.92 | CTSS (0.60) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL19962115 | 0.89 | CTSS (0.55) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL20427678 | 0.88 | CTSS (0.54) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL16681983 | 0.88 | CTSS (0.54) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL18180230 | 0.88 | CTSS (0.54) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL15914664 | 0.88 | CTSS (0.58) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL15886501 | 0.88 | CTSS (0.58) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL18181215 | 0.87 | ACE (0.52) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL18180261 | 0.86 | CTSS (0.46) | CTSSCTSKCTSLCTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210322416-A1 | ANTIVIRAL COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210322416-A1 | ANTIVIRAL COMPOUNDS | ZC3HAV1, ZC3HAV1L, CD4 | CTSS 858/4885CTSK 1715/4885CTSL 1663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.