Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645855 | 0.80 | POLB (0.40) | CYP1A2MAPK8ALDH1A1MEN1KMT2A | |
| SCHEMBL4617524 | 0.78 | CYP1A2 (0.38) | FTOCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL10969861 | 0.77 | FTO (0.40) | FTOCYP1A2DYRK1ADYRK1BALDH1A1 | |
| SCHEMBL20843986 | 0.77 | CYP1A2 (0.45) | CYP1A2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL8116805 | 0.77 | LRRK2 (0.39) | FTOCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL3169433 | 0.77 | FTO (0.40) | FTOCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL20630524 | 0.76 | FTO (0.37) | FTOCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL28223670 | 0.76 | NPSR1 (0.45) | DYRK1ADYRK1BALDH1A1MEN1KMT2A | |
| SCHEMBL30067848 | 0.75 | HASPIN (0.37) | FTOCYP1A2DYRK1AALDH1A1MEN1 | |
| SCHEMBL17541424 | 0.75 | FTO (0.39) | FTOCYP1A2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113009014-B | High performance liquid detection method for 2-methoxy-5-fluorouracil impurities | 上海旭东海普药业有限公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |
| CN-113009014-A | High performance liquid detection method for 2-methoxy-5-fluorouracil impurity | 上海旭东海普药业有限公司 | 2021-06-22 | — | — | CN | disclosed |