Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174711 | 0.74 | — | — | |
| SCHEMBL16267051 | 0.72 | PLA2G4A (0.37) | ALDH1A1KMT2A | |
| SCHEMBL23937806 | 0.69 | HTR2A (0.34) | HTR2AHTR2CHPGDALDH1A1KMT2A | |
| SCHEMBL16267053 | 0.65 | ASAH1 (0.41) | MEN1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL13217 | 0.64 | RECQL (0.61) | MEN1KMT2ARECQL | |
| SCHEMBL21295080 | 0.63 | PDE7A (0.40) | HPGDALDH1A1 | |
| SCHEMBL21285480 | 0.61 | MAPT (0.40) | HTR2AHTR2CHASPINMEN1KMT2A | |
| SCHEMBL23206121 | 0.61 | HTR2C (0.46) | HTR2AHTR2CHASPINCYP11B2HTT | |
| SCHEMBL21501930 | 0.61 | HASPIN (0.49) | HTR2AHTR2CHASPINHPGDALDH1A1 | |
| SCHEMBL18237382 | 0.61 | HASPIN (0.36) | HASPINCYP11B2HTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |