Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17827121 | 0.84 | PIK3CB (0.34) | BRD9APPPDE10APIK3CBGRM5 | |
| SCHEMBL23937774 | 0.76 | ELANE (0.34) | — | |
| SCHEMBL16511362 | 0.76 | BRD9 (0.36) | BRD9APPPIK3CBGRM5 | |
| SCHEMBL13573819 | 0.74 | PIK3CB (0.44) | BRD9APPPIK3CBGRM5DYRK1A | |
| SCHEMBL30912393 | 0.74 | MAPK1 (0.39) | BRD9APPPIK3CBGRM5 | |
| SCHEMBL13573893 | 0.74 | MAPK1 (0.39) | BRD9APPPIK3CBGRM5 | |
| SCHEMBL20673864 | 0.74 | BRD9 (0.35) | BRD9APPPIK3CBGRM5 | |
| SCHEMBL12032587 | 0.70 | PIK3CB (0.34) | BRD9APPPIK3CBGRM5 | |
| SCHEMBL256368 | 0.70 | ELANE (0.42) | BRD9PIK3CBGRM5 | |
| SCHEMBL17122511 | 0.70 | FGFR3 (0.38) | APPPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |