Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23937785 | 0.71 | — | — | |
| SCHEMBL21958538 | 0.67 | — | — | |
| SCHEMBL21958541 | 0.66 | ADORA2A (0.40) | — | |
| SCHEMBL21958622 | 0.66 | — | — | |
| SCHEMBL23937782 | 0.66 | CNOT7 (0.30) | — | |
| SCHEMBL21958542 | 0.62 | ADORA3 (0.34) | — | |
| SCHEMBL20674203 | 0.61 | PDE10A (0.33) | — | |
| SCHEMBL20631028 | 0.58 | — | — | |
| SCHEMBL5921963 | 0.52 | — | — | |
| SCHEMBL21748858 | 0.52 | OPRL1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |