Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976940 | 0.97 | — | — | |
| SCHEMBL8225505 | 0.91 | — | — | |
| SCHEMBL19198191 | 0.91 | ALDH1A1 (0.44) | SMN1; SMN2CXCR4ALDH1A1TSHRCYP2C9 | |
| SCHEMBL12715 | 0.91 | — | — | |
| SCHEMBL19632208 | 0.91 | ALDH1A1 (0.44) | SMN1; SMN2CXCR4ALDH1A1TSHRCYP2C9 | |
| SCHEMBL1099645 | 0.91 | — | — | |
| SCHEMBL22580339 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2CXCR4ALDH1A1TSHRSLC6A1 | |
| SCHEMBL22595745 | 0.88 | ALDH1A1 (0.50) | SMN1; SMN2CXCR4ALDH1A1TSHRSLC6A1 | |
| SCHEMBL21039971 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2CXCR4ALDH1A1TSHRCYP2C9 | |
| SCHEMBL21017164 | 0.88 | ALDH1A1 (0.50) | SMN1; SMN2CXCR4ALDH1A1TSHRSLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297438-B1 | CCR2 MODULATORS | CHEMOCENTRYX INC (US) | 2021-10-20 | — | — | EP | disclosed |