Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24007285 | 0.79 | CES2 (0.32) | CES2CES1KEAP1IDO1 | |
| SCHEMBL23938344 | 0.78 | MAP2K2 (0.36) | ALDH1A1IDO1GAA | |
| SCHEMBL15489581 | 0.75 | CES2 (0.52) | CES2CES1CA3CA6CA5A | |
| SCHEMBL12225512 | 0.75 | CES2 (0.52) | CES2CES1CA3CA6CA5A | |
| SCHEMBL801104 | 0.73 | CES2 (0.50) | CES2CES1CA3CA6CA5A | |
| SCHEMBL84165 | 0.73 | CES2 (0.50) | CES2CES1CA3CA6CA5A | |
| Hydrochloric Acid SCHEMBL7963311 | 0.73 | CES2 (0.50) | CES2CES1CA3CA6CA5A | |
| SCHEMBL246382 | 0.73 | CES2 (0.61) | CES2CES1KEAP1ALDH1A1TAS1R3 | |
| SCHEMBL16359664 | 0.73 | CES2 (0.50) | CES2CES1CA3CA6CA5A | |
| SCHEMBL24417687 | 0.72 | CYP11B1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297438-B1 | CCR2 MODULATORS | CHEMOCENTRYX INC (US) | 2021-10-20 | — | — | EP | disclosed |