Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.53 |
| ▸ | TACR1 | P25103 | 3/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18253113 | 1.00 | CCR2 (0.53) | CCR2KCNH2TACR1OPRL1 | |
| SCHEMBL19443148 | 1.00 | CCR2 (0.53) | CCR2KCNH2TACR1OPRL1 | |
| SCHEMBL18253118 | 0.91 | CCR2 (0.59) | CCR2KCNH2TACR1 | |
| SCHEMBL18253094 | 0.90 | CCR2 (0.57) | CCR2KCNH2TACR1 | |
| SCHEMBL18244776 | 0.89 | CCR2 (0.64) | CCR2KCNH2TACR1 | |
| SCHEMBL23938568 | 0.89 | CCR2 (0.64) | CCR2KCNH2TACR1 | |
| SCHEMBL18245003 | 0.89 | CCR2 (0.64) | CCR2KCNH2TACR1 | |
| SCHEMBL23938462 | 0.89 | CCR2 (0.55) | CCR2KCNH2TACR1OPRL1 | |
| SCHEMBL21900433 | 0.89 | CCR2 (0.55) | CCR2KCNH2TACR1OPRL1 | |
| SCHEMBL18253111 | 0.89 | CCR2 (0.55) | CCR2KCNH2TACR1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297438-B1 | CCR2 MODULATORS | CHEMOCENTRYX INC (US) | 2021-10-20 | — | — | EP | disclosed |