Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 9/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 9/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.55 |
| ▸ | CDK1 | P06493 | 6/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.55 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.55 |
| ▸ | CDK4 | P11802 | 3/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.55 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.34 |
| ▸ | PRKCG | P05129 | 2/20 | 0.34 |
| ▸ | PRKCB | P05771 | 2/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | PRKCH | P24723 | 2/20 | 0.34 |
| ▸ | PRKCI | P41743 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987882 | 0.75 | CDK5 (0.63) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL15426067 | 0.74 | CDK5 (0.73) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL3424550 | 0.72 | CDK5 (0.55) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL3425853 | 0.67 | CDK5 (0.57) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL3425857 | 0.67 | CDK5 (0.57) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL3426570 | 0.66 | CDK5 (0.77) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL3426574 | 0.66 | CDK5 (0.77) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL13341095 | 0.66 | CDK5 (0.77) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL17166885 | 0.63 | CDK5 (0.57) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL3424813 | 0.58 | CDK5 (0.67) | CDK5CDK5R1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515559-B1 | COMPOSITIONS AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND TREATMENT OF AML USING USP10 BIOMARKERS AND MODULATORS | DANA FARBER CANCER INST INC (US) | 2025-05-21 | — | — | EP | disclosed |
| US-20210324478-A1 | COMPOSITIONS AND METHODS FOR IDENTIFICATION ASSESSMENT, PREVENTION, AND TREATMENT OF EWING SARCOMA USING TP53 DEPENDENCY BIOMARKERS AND MODULATORS | DANA-FARBER CANCER INSTITUTE, INC. | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210324478-A1 | COMPOSITIONS AND METHODS FOR IDENTIFICATION ASSESSMENT, PREVENTION, AND TREATMENT OF EWING SARCOMA USING TP53 DEPENDENCY BIOMARKERS AND MODULATORS | TP53, MDM4, EWSR1 | CDK5 673/4885CDK5R1 868/4885CCNB2 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.