Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4111089 | 0.86 | CYP2A13 (0.63) | CYP2A13MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL17724132 | 0.81 | CYP2A13 (0.71) | CYP2A13MEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL22479885 | 0.81 | CYP2A13 (0.62) | CYP2A13MAPTMEN1KMT2ACXCR4 | |
| SCHEMBL249086 | 0.78 | CYP2A13 (0.61) | CYP2A13MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL26505561 | 0.78 | MAPT (0.51) | CYP2A13MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL19532823 | 0.78 | CYP2A13 (0.56) | CYP2A13MEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL19542005 | 0.77 | CYP2A13 (0.56) | CYP2A13MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL26832821 | 0.75 | ALDH1A1 (0.48) | MAPTMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL29417692 | 0.75 | CYP2A13 (0.56) | CYP2A13MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL17724305 | 0.75 | CYP2A13 (0.56) | CYP2A13MAPTMEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |
| EP-3643709-B1 | ISOINDOLINE DERIVATIVE, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | KANGPU BIOPHARMACEUTICALS LTD (CN) | 2021-10-20 | — | — | EP | disclosed |