⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21894530 | 0.64 | — | — | |
| SCHEMBL30593705 | 0.59 | — | — | |
| SCHEMBL25481494 | 0.50 | — | — | |
| SCHEMBL20748212 | 0.50 | — | — | |
| SCHEMBL21471626 | 0.50 | — | — | |
| SCHEMBL13683847 | 0.48 | — | — | |
| SCHEMBL9988089 | 0.48 | — | — | |
| SCHEMBL10694456 | 0.46 | — | — | |
| SCHEMBL9934533 | 0.46 | ALDH1A1 (0.33) | — | |
| SCHEMBL23881943 | 0.46 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445914-B1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INT (DE) | 2015-07-22 | — | — | EP | disclosed |
| EP-2225238-B1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZOÝ1,2- ¨IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INT (DE) | 2014-09-03 | — | — | EP | disclosed |
| CN-102875416-B | Chiral compound | LUO MEI | 2014-04-16 | — | — | CN | disclosed |
| EP-2445909-B1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INT (DE) | 2013-11-13 | — | — | EP | disclosed |
| US-8575360-B2 | Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid amides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-11-05 | — | — | US | disclosed |
| US-8552205-B2 | Derivatives of 6,7-dihydro-5H-imidazo[1,2-alpha]imidazole-3-carboxylic acid amides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-08 | — | — | US | disclosed |
| US-8481750-B2 | Derivatives of 6,7-dihydro-5H-imidazo[1,2-α]imidazole-3-carboxylic acid amides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-09 | — | — | US | disclosed |
| CN-102875416-A | Chiral compound | LUO MEI | 2013-01-16 | — | — | CN | disclosed |
| US-20120252817-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-04 | — | — | US | disclosed |
| US-20120178734-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-07-12 | — | — | US | disclosed |
| WO-1995030901-A1 | METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1995-11-16 | — | — | WO | disclosed |
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |
| US-4971958-A | CALCIUM METABOLISM | BOEHRINGER MANNHEIM GMBH (DE) | 1990-11-20 | — | — | US | disclosed |
| EP-0273190-A1 | Diphosphoric acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |
| EP-0022538-B1 | PROCESS FOR PREPARING NAPHTHALENESULPHOCHLORIDE | BAYER AG (DE) | 1982-09-15 | — | — | EP | disclosed |
| US-4339396-A | Process for the preparation of naphthalenesulphonyl chloride | BAYER AKTIENGESELLSCHAFT (DE) | 1982-07-13 | — | — | US | disclosed |
| EP-0022538-A2 | Process for preparing naphthalenesulphochloride | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| US-4163857-A | DRUGS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-08-07 | — | — | US | disclosed |
| US-4111918-A | POLYPARABANIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |
| US-3939125-A | CURABLE | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |