Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Olitigaltin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 known ✓ | P17931 | 20/20 | 1.00 |
| ▸ | LGALS1 | P09382 | 13/20 | 1.00 |
| ▸ | LGALS8 | O00214 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Olitigaltin SCHEMBL18556517 | 1.00 | LGALS3 (1.00) | LGALS3LGALS1LGALS8 | |
| Olitigaltin SCHEMBL19630648 | 1.00 | LGALS3 (1.00) | LGALS3LGALS1LGALS8 | |
| Olitigaltin SCHEMBL15657272 | 1.00 | LGALS3 (1.00) | LGALS3LGALS1LGALS8 | |
| Olitigaltin SCHEMBL19678765 | 1.00 | LGALS3 (1.00) | LGALS3LGALS1LGALS8 | |
| Olitigaltin SCHEMBL17432857 | 1.00 | LGALS3 (1.00) | LGALS3LGALS1LGALS8 | |
| Olitigaltin SCHEMBL19680604 | 1.00 | LGALS3 (1.00) | LGALS3LGALS1LGALS8 | |
| Olitigaltin SCHEMBL19848047 | 1.00 | LGALS3 (1.00) | LGALS3LGALS1LGALS8 | |
| Olitigaltin SCHEMBL19005446 | 1.00 | LGALS3 (1.00) | LGALS3LGALS1LGALS8 | |
| Olitigaltin SCHEMBL17163850 | 1.00 | LGALS3 (1.00) | LGALS3LGALS1LGALS8 | |
| Olitigaltin SCHEMBL17935223 | 1.00 | LGALS3 (1.00) | LGALS3LGALS1LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896075-A1 | POLYMORPHIC FORMS AND PROCESS | Galecto Biotech AB (DK) | 2021-10-20 | — | — | EP | disclosed |