Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.37 |
| ▸ | LARS1 | Q9P2J5 | 5/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23939724 | 0.91 | LARS1 (0.43) | RPS6KA1LARS1EPAS1 | |
| SCHEMBL469420 | 0.89 | LARS1 (0.45) | RPS6KA1LARS1 | |
| SCHEMBL469421 | 0.89 | LARS1 (0.45) | RPS6KA1LARS1 | |
| SCHEMBL469422 | 0.89 | LARS1 (0.45) | RPS6KA1LARS1 | |
| SCHEMBL23939741 | 0.88 | LARS1 (0.46) | LARS1 | |
| SCHEMBL19017151 | 0.88 | LARS1 (0.47) | LARS1 | |
| SCHEMBL23939723 | 0.81 | RPS6KA1 (0.40) | RPS6KA1EPHX2 | |
| SCHEMBL19672999 | 0.81 | RPS6KA1 (0.40) | RPS6KA1EPHX2 | |
| SCHEMBL21570015 | 0.79 | LARS1 (0.43) | RPS6KA1LARS1 | |
| SCHEMBL23939742 | 0.78 | LARS1 (0.47) | LARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251678-B1 | BENZOXABOROLE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | ANACOR PHARMACEUTICALS INC (US) | 2021-10-20 | — | — | EP | disclosed |