Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21427331 | 0.73 | APLNR (0.42) | APLNR | |
| SCHEMBL20054515 | 0.71 | APLNR (0.32) | APLNR | |
| SCHEMBL25773620 | 0.69 | — | — | |
| SCHEMBL24761183 | 0.69 | APLNR (0.35) | APLNR | |
| SCHEMBL14490646 | 0.67 | — | — | |
| SCHEMBL18781236 | 0.67 | — | — | |
| SCHEMBL8312869 | 0.67 | — | — | |
| SCHEMBL26646186 | 0.67 | CYP2C9 (0.38) | APLNR | |
| SCHEMBL25419059 | 0.65 | — | — | |
| SCHEMBL24354653 | 0.63 | APLNR (0.31) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3985001-A1 | PHARMACEUTICAL COMPOSITION USEFUL IN INHIBITING IDH1 | Les Laboratoires Servier SAS (FR) | 2022-04-20 | — | — | EP | disclosed |
| EP-3447052-B1 | METHODS OF PREPARING NEW IDH1 INHIBITORS | LES LABORATOIRES SERVIER SAS (FR) | 2021-10-20 | — | — | EP | disclosed |