Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269461 | 0.91 | — | — | |
| SCHEMBL24668139 | 0.87 | CYP1A2 (0.31) | — | |
| SCHEMBL11279005 | 0.80 | — | — | |
| SCHEMBL10896704 | 0.73 | KMT2A (0.46) | KMT2ACYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL28684669 | 0.73 | KMT2A (0.46) | KMT2ACYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL19303361 | 0.73 | KMT2A (0.46) | KMT2ACYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL13184894 | 0.73 | KMT2A (0.46) | KMT2ACYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL29828938 | 0.73 | KMT2A (0.46) | KMT2ACYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL21633008 | 0.73 | KMT2A (0.46) | KMT2ACYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL10382344 | 0.73 | KMT2A (0.46) | KMT2ACYP2C9TSHRCYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3447052-B1 | METHODS OF PREPARING NEW IDH1 INHIBITORS | LES LABORATOIRES SERVIER SAS (FR) | 2021-10-20 | — | — | EP | disclosed |