SCHEMBL11279005

SCHEMBL11279005

C=C1CCC(C)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8269461 0.84
SCHEMBL23940451 0.80 KMT2A (0.37)
SCHEMBL10029100 0.74
SCHEMBL24668139 0.70 CYP1A2 (0.31)
SCHEMBL13322945 0.67
SCHEMBL7618464 0.67
SCHEMBL6977167 0.67
SCHEMBL4086483 0.67
SCHEMBL666843 0.67
SCHEMBL19457696 0.67 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3692040-B1 CHEMICAL COMPOUNDS GLAXOSMITHKLINE IP DEV LTD (GB) 2022-12-28 EP disclosed
EP-3280412-B1 PYRROLIDONE CARBOXYLIC ACID (PCA) FOR OPHTHALMIC USE LABORATORI BALDACCI SPA (IT) 2019-08-14 EP disclosed
US-20170183318-A1 AMIDE COMPOUNDS, METHODS FOR PREPARATION, AND USE THEREOF AS AGENTS FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY RNA- AND/OR DNA-CONTAINING VIRUSES, AND CONCOMITANT DISEASES OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2017-06-29 US disclosed
EP-1794182-B1 COMPOUNDS THAT MODULATE TRH ACTIONS AND INHIBIT THE TRH-DEGRADING ENZYME TRINITY COLLEGE DUBLIN (IE) 2015-06-03 EP disclosed
US-20130217702-A1 INDOLE DERIVATIVES RICHTER GEDEON NYRT. 2013-08-22 US disclosed
US-7781431-B2 Thienopyrroles as antiviral agents ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) 2010-08-24 US disclosed
EP-1261624-B1 TRH-LIKE PEPTIDE DERIVATIVES AS INHIBITORS OF THE TRH-DEGRADING ECTOENZYME TRINITY COLLEGE DUBLIN (IE) 2010-07-07 EP disclosed
US-7713935-B2 Compounds that modulate TRH actions THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) 2010-05-11 US disclosed
US-7683365-B2 Image pickup device FUJIFILM CORPORATION (JP) 2010-03-23 US disclosed
US-20090036443-A1 Thienopyrroles as antiviral agents ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI (IT) 2009-02-05 US disclosed
US-7378397-B2 TRH-degrading ectoenzyme inhibitors THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) 2008-05-27 US disclosed
US-20070265202-A1 Compounds That Modulate Trh Actions THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE O (IE) 2007-11-15 US disclosed
US-4353913-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DE) 1982-10-12 US disclosed
EP-0010242-B1 BENZIMIDAZOLYL-2-CARBAMIC ACID ESTERS, MEDICAMENTS BASED THEREON AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1982-09-29 EP disclosed
US-4287199-A USEFUL AS ANTHELMINITICS BAYER AKTIENGESELLSCHAFT (DE) 1981-09-01 US disclosed
EP-0010242-A1 Benzimidazolyl-2-carbamic acid esters, medicaments based thereon and process for their preparation BAYER AG (DE) 1980-04-30 EP disclosed