Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 20/20 | 0.61 |
| ▸ | BMPR1A | P36894 | 20/20 | 0.61 |
| ▸ | TGFBR1 | P36897 | 20/20 | 0.61 |
| ▸ | ACVRL1 | P37023 | 20/20 | 0.61 |
| ▸ | ACVR1 | Q04771 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19807060 | 1.00 | BMPR1B (0.61) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL19807041 | 0.87 | BMPR1B (0.73) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL23940733 | 0.87 | BMPR1B (0.73) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL23940717 | 0.86 | BMPR1B (0.61) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL23940672 | 0.85 | BMPR1B (0.62) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL19806965 | 0.85 | BMPR1B (0.62) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL19806894 | 0.85 | BMPR1B (0.61) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL23940734 | 0.85 | BMPR1B (0.61) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL23940505 | 0.84 | BMPR1B (0.61) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL19807028 | 0.84 | BMPR1B (0.61) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487851-B1 | AMINOPYRIDINE DERIVATIVES AND THEIR USE AS SELECTIVE ALK-2 INHIBITORS | NOVARTIS AG (CH) | 2021-10-20 | — | — | EP | disclosed |