SCHEMBL2394224

SCHEMBL2394224

NC(CS(=O)(=O)C[C@H](N)C(=O)O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 0.55
GCLC P48506 1/20 0.48
PTGS1 P23219 1/20 0.48
SLC7A11 Q9UPY5 1/20 0.48
PMP22 Q01453 2/20 0.46
KYNU Q16719 2/20 0.46
SLC1A1 P43005 4/20 0.44
SLC1A3 P43003 3/20 0.44
SLC1A2 P43004 3/20 0.44
GSR P00390 2/20 0.44
GRIK1 P39086 2/20 0.44
GRIK2 Q13002 2/20 0.44
GRM1 Q13255 2/20 0.44
GRM2 Q14416 2/20 0.44
SLC7A5 Q01650 1/20 0.44
GRM8 O00222 1/20 0.44
GRM6 O15303 1/20 0.44
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
CYP1A2 P05177 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13900351 0.87 NOS2 (0.55) NOS2GCLCPTGS1SLC7A11PMP22
SCHEMBL8951292 0.87 NOS2 (0.55) NOS2GCLCPTGS1SLC7A11PMP22
SCHEMBL27926048 0.85 GCLC (0.67) NOS2GCLCPTGS1SLC7A11PMP22
SCHEMBL18893866 0.85 POLB (0.52) NOS2GCLCPTGS1SLC7A11PMP22
SCHEMBL155592 0.85 POLB (0.52) NOS2GCLCPTGS1SLC7A11PMP22
Hydrochloric Acid SCHEMBL10649337 0.84 NOS2 (0.47) NOS2GCLCPTGS1SLC7A11PMP22
SCHEMBL624998 0.84 NOS2 (0.56) NOS2GCLCPTGS1SLC7A11PMP22
SCHEMBL27814297 0.84 NOS2 (0.56) NOS2GCLCPTGS1SLC7A11PMP22
SCHEMBL2244806 0.84 NOS2 (0.56) NOS2GCLCPTGS1SLC7A11PMP22
SCHEMBL20077378 0.82 NOS2 (0.46) NOS2GCLCPTGS1SLC7A11PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9528114-B2 Method for amplifying locus in bacterial cell DANISCO US INC. (US) 2016-12-27 US disclosed
CN-101981193-B The method of amplifying locus in bacterial cell DANISCO US INC. (US) 2016-05-11 CN disclosed
EP-2257629-B1 METHOD FOR AMPLIFYING LOCUS IN BACTERIAL CELL DANISCO US INC (US) 2016-03-16 EP disclosed
WO-2014025686-A1 COMPOSITIONS AND METHODS FOR TREATING A KERATIN BASED SUBSTRATE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2014-02-13 WO disclosed
US-20110229938-A1 Method For Amplifying Locus In Bacterial Cell DANISCO US INC. 2011-09-22 US disclosed
EP-2257629-A1 METHOD FOR AMPLIFYING LOCUS IN BACTERIAL CELL Danisco US Inc. (US) 2010-12-08 EP disclosed
WO-2009120929-A1 METHOD FOR AMPLIFYING LOCUS IN BACTERIAL CELL DANISCO US INC., GENENCOR DIVISION (US) 2009-10-01 WO disclosed