Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.94 |
| ▸ | HMGCR | P04035 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL30338259 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL1939439 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28323708 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28197467 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL7608512 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28064645 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL3417188 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL1331942 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL725546 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL842 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 686 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119955492-A | Gel blocking agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119955491-A | Self-repairing gel plugging agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119701927-A | Special atmosphere treated propane dehydrogenation propylene preparation supported catalyst and preparation method thereof | 中国科学院大连化学物理研究所 | 2025-03-28 | — | — | CN | claimed |
| CN-119588371-A | Coated catalyst for preparing lactone by dehydrocyclization of diol, preparation method and application | 万华化学集团股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-117209657-B | Polymer gel plugging agent suitable for tight fractured reservoir and preparation method thereof | 西南石油大学 | 2024-07-19 | — | — | CN | claimed |
| CN-118007183-B | Electrocatalytic material, electrochemical catalytic system, and preparation and application thereof | 东华大学 | 2024-07-12 | — | — | CN | claimed |
| CN-114678545-B | Electrocatalytic material and preparation method and application thereof | 中南大学 | 2024-05-10 | — | — | CN | claimed |
| CN-118007183-A | Electrocatalytic material, electrochemical catalytic system, and preparation and application thereof | 东华大学 | 2024-05-10 | — | — | CN | claimed |
| CN-115779885-B | Light hydrocarbon dehydrogenation catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117920191-A | Carrier of alkane dehydrogenation catalyst capable of rapidly clearing coke, preparation method of carrier, catalyst, preparation method and application of catalyst | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| US-6051670-A | CONSISTS OF WATER SOLUBLE POLYMER CONTAINING NITROGEN CONTAINING OLEFINIC MONOMER, A CROSSLINKING AGENT AND A LIQUID | PHILLIPS PETROLEUM COMPANY (US) | 2000-04-18 | — | — | US | claimed |
| US-5883210-A | GELLING COMPOSITION FOR OIL FIELDS, WATER SOLUBLE POLYMER, CROSSLINKING AGENT FOR DRILLING FLUIDS | PHILLIPS PETROLEUM COMPANY (US) | 1999-03-16 | — | — | US | claimed |
| WO-1997022638-A1 | COMPOSITIONS AND PROCESSES FOR TREATING SUBTERRANEAN FORMATIONS | PHILLIPS PETROLEUM COMPANY (US) | 1997-06-26 | — | — | WO | claimed |
| EP-0668432-A2 | Process for treating oil-bearing formation | PHILLIPS PETROLEUM COMPANY (US) | 1995-08-23 | — | — | EP | claimed |
| US-5423380-A | Adding crosslinking agent intermittently to stream of aqueous solution of gellable polymer injected into subterranean formation | PHILLIPS PETROLEUM COMPANY (US) | 1995-06-13 | — | — | US | claimed |
| US-5340834-A | Adding chromium citrate to diet | STITT PAUL A (US) | 1994-08-23 | — | — | US | claimed |
| US-5268112-A | Silicates, colloidal silica and(or) crosslinked polymer and a base | UNION OIL COMPANY OF CALIFORNIA (US) | 1993-12-07 | — | — | US | claimed |
| US-5225090-A | Cationic polyacrylamides, reducing permeability of subterranean formations | UNION OIL COMPANY OF CALIFORNIA (US) | 1993-07-06 | — | — | US | claimed |
| US-5213446-A | Adding a crosslinkable polymer and a crosslinking agent | UNION OIL COMPANY OF CALIFORNIA (US) | 1993-05-25 | — | — | US | claimed |
| US-5161615-A | Injecting hydrophilic polymer-containing organic carrier fluid into formation, injecting crosslinking agent-containing fluid, gel formation | UNION OIL COMPANY OF CALIFORNIA (US) | 1992-11-10 | — | — | US | claimed |