Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 16/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23943822 | 0.85 | EGLN2 (0.40) | EGLN2ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL4814284 | 0.83 | ENPP1 (0.35) | ALDH1A1KMT2AMEN1GAAPDE2A | |
| SCHEMBL23944462 | 0.80 | EGLN2 (0.39) | EGLN2ALDH1A1KMT2APDE2APOLB | |
| SCHEMBL23944159 | 0.80 | EGLN2 (0.39) | EGLN2PDE2A | |
| SCHEMBL4820773 | 0.79 | ENPP1 (0.35) | ALDH1A1KMT2AMEN1GAAPOLB | |
| SCHEMBL23943830 | 0.77 | EGLN2 (0.30) | EGLN2ALDH1A1KMT2APOLBTSHR | |
| SCHEMBL23943823 | 0.76 | EGLN2 (0.31) | EGLN2ALDH1A1KMT2APOLBTSHR | |
| SCHEMBL4820523 | 0.74 | ENPP1 (0.36) | ALDH1A1KMT2AMEN1GAAGFER | |
| SCHEMBL23925484 | 0.73 | EGLN2 (0.48) | EGLN2ALDH1A1KMT2APOLBTSHR | |
| SCHEMBL23944197 | 0.73 | EGLN2 (0.40) | EGLN2ALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211408-A1 | SUBSTITUTED {1,2,4,} TRIAZOLO{1,5-A} PYRIMIDINE COMPOUNDS AND USE IN STABILIZING MICROTUBULES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2021-10-21 | — | — | WO | disclosed |