SCHEMBL23944835

SCHEMBL23944835

CC(C)c1nc(-c2ccc3c(c2)C2C=CC=CC2O3)nc(-c2ccc3ccccc3c2)n1

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.32
S1PR1 P21453 1/20 0.31
UTRN P46939 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
LIPE Q05469 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21662100 0.86 MEN1 (0.33) S1PR1MEN1CYP1A2KMT2AHSD17B10
SCHEMBL23944836 0.82 ADORA2A (0.32) MEN1ALDH1A1CYP1A2KMT2ASMN1; SMN2
SCHEMBL24973903 0.81 PDE9A (0.33) CYP1A2SMN1; SMN2
SCHEMBL179257 0.77 HSD17B1 (0.35)
SCHEMBL20152493 0.76 IKBKB (0.42) NR1H4BCHEACHELIPEKDM4E
SCHEMBL25834415 0.74 PIM1 (0.30) KDM4EMEN1ALDH1A1TP53CYP1A2
SCHEMBL12640770 0.74 ESR1 (0.33)
SCHEMBL21662098 0.72 ADORA2A (0.31)
SCHEMBL23776067 0.72 MEN1 (0.50) KDM4EMEN1ALDH1A1TP53CYP1A2
SCHEMBL21662067 0.71 ADORA2A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328154-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed