SCHEMBL23944846

SCHEMBL23944846

c1ccc(-c2nc3ccc4ccc5cc(-c6ccc(-c7ccc8c9ccccc9c9ccccc9c8c7)c7ccccc67)ccc5c4c3o2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.45
ESR2 Q92731 2/20 0.45
DHODH Q02127 1/20 0.44
ELANE P08246 1/20 0.40
NPC1 O15118 5/20 0.36
RAB9A P51151 5/20 0.36
PIK3CA P42336 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
VSIR Q9H7M9 2/20 0.36
GPR119 Q8TDV5 1/20 0.36
SMN1; SMN2 Q16637 4/20 0.35
KDM4E B2RXH2 3/20 0.35
CASP3 P42574 2/20 0.35
SENP7 Q9BQF6 2/20 0.35
SENP6 Q9GZR1 2/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.35
SENP8 Q96LD8 1/20 0.35
BACE1 P56817 1/20 0.35
ALDH1A1 P00352 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22880145 0.94 DHODH (0.45) ESR1ESR2DHODHELANENPC1
SCHEMBL22879947 0.94 DHODH (0.47) ESR1ESR2DHODHELANENPC1
SCHEMBL22880323 0.90 ESR1 (0.43) ESR1ESR2DHODHELANENPC1
SCHEMBL22880531 0.90 DHODH (0.47) ESR1ESR2DHODHELANENPC1
SCHEMBL22880307 0.90 ESR1 (0.45) ESR1ESR2DHODHELANENPC1
SCHEMBL22880575 0.89 DHODH (0.44) ESR1ESR2DHODHELANENPC1
SCHEMBL21167899 0.89 ESR1 (0.43) ESR1ESR2DHODHELANENPC1
SCHEMBL21158010 0.88 ESR1 (0.42) ESR1ESR2DHODHELANENPC1
SCHEMBL22880605 0.87 ESR1 (0.46) ESR1ESR2DHODHELANENPC1
SCHEMBL22880577 0.87 DHODH (0.48) ESR1ESR2DHODHELANENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793075-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-17 US disclosed
US-11793075-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-17 US disclosed
US-11588112-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-02-21 US disclosed
US-20220020931-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-01-20 US disclosed
US-20210359216-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-11-18 US disclosed
US-20210328154-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220020931-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, SOD1, LIMS1 ESR1 1254/4885ESR2 1220/4885DHODH 3303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.