Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | MPC2 | O95563 | 2/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19217571 | 0.89 | PPARG (0.54) | PPARGMPC2CYP2C8CYP2C9POLB | |
| SCHEMBL22226858 | 0.88 | PPARG (0.53) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL19217749 | 0.81 | PPARG (0.55) | LMNAPPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL936979 | 0.80 | PPARG (0.79) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL21504732 | 0.77 | PPARG (0.68) | LMNAPPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6327817 | 0.74 | LMNA (0.73) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL8282082 | 0.74 | LMNA (0.53) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL25833062 | 0.73 | PPARG (0.54) | LMNAMAPK1CASP3SENP7SENP6 | |
| SCHEMBL935850 | 0.70 | PPARG (0.77) | PPARGMPC2CYP2C8CYP2C9TP53 | |
| SCHEMBL19217624 | 0.70 | FFAR1 (0.46) | L3MBTL1NR4A2MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021212054-A1 | METHODS AND COMPOSITIONS FOR TREATING SUBJECTS WITH METABOLIC DISORDERS AND CORONAVIRUS INFECTIONS | CIRIUS THERAPEUTICS, INC. (US) | 2021-10-21 | — | — | WO | disclosed |