SCHEMBL23946310

SCHEMBL23946310

Cc1nc(-c2ccccc2)c2c(-c3ccccc3)cccc2n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.51
TDP1 Q9NUW8 2/20 0.44
PDE10A Q9Y233 2/20 0.42
KDM4E B2RXH2 6/20 0.41
ALDH1A1 P00352 5/20 0.41
GAA P10253 2/20 0.41
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
DHODH Q02127 1/20 0.40
NTRK1 P04629 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
POLB P06746 2/20 0.40
HPGD P15428 2/20 0.40
CYP1A2 P05177 1/20 0.40
TNNI3 P19429 1/20 0.40
CYP2C19 P33261 1/20 0.40
TNNT2 P45379 1/20 0.40
TNNC1 P63316 1/20 0.40
RUNX1 Q01196 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23946292 0.97 KCNH2 (0.49) KCNH2TDP1PDE10AKDM4EALDH1A1
SCHEMBL23946340 0.93 KCNH2 (0.46) KCNH2TDP1PDE10AKDM4EALDH1A1
SCHEMBL23946343 0.91 KCNH2 (0.44) KCNH2TDP1PDE10AKDM4EALDH1A1
SCHEMBL23946327 0.87 ADORA2A (0.45) KCNH2TDP1PDE10AKDM4EALDH1A1
SCHEMBL23946297 0.86 KCNH2 (0.41) KCNH2TDP1PDE10AKDM4EALDH1A1
SCHEMBL12169929 0.83 KCNH2 (0.51) KCNH2TDP1KDM4EALDH1A1GAA
SCHEMBL23946302 0.82 KDM4E (0.39) KCNH2TDP1PDE10AKDM4EALDH1A1
SCHEMBL2261387 0.81 KCNH2 (0.50) KCNH2KDM4EALDH1A1L3MBTL1MEN1
SCHEMBL5988414 0.81 MEN1 (0.50) KCNH2LMNAL3MBTL1MEN1KMT2A
SCHEMBL19792777 0.80 MAPT (0.44) KCNH2KDM4EALDH1A1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES IDO1, IDO2, AZI2 KCNH2 8/4885TDP1 3399/4885PDE10A 704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.