SCHEMBL23946343

SCHEMBL23946343

Cc1nc(-c2ccccc2)c2c(-c3cccc(-c4ccccc4)c3)cccc2n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.44
PDE10A Q9Y233 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
DHODH Q02127 2/20 0.39
L3MBTL1 Q9Y468 4/20 0.38
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 3/20 0.38
GAA P10253 2/20 0.38
LMNA P02545 2/20 0.38
ADORA1 P30542 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
MAPT P10636 1/20 0.37
APEX1 P27695 1/20 0.37
NPY5R Q15761 3/20 0.36
POLB P06746 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP1A2 P05177 1/20 0.36
HPGD P15428 1/20 0.36
TNNI3 P19429 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23946292 0.91 KCNH2 (0.49) KCNH2PDE10ATDP1DHODHL3MBTL1
SCHEMBL23946310 0.91 KCNH2 (0.51) KCNH2PDE10ATDP1DHODHL3MBTL1
SCHEMBL23946327 0.87 ADORA2A (0.45) KCNH2PDE10ATDP1DHODHL3MBTL1
SCHEMBL23946340 0.84 KCNH2 (0.46) KCNH2PDE10ATDP1DHODHL3MBTL1
SCHEMBL23946297 0.81 KCNH2 (0.41) KCNH2PDE10ATDP1DHODHL3MBTL1
SCHEMBL20233959 0.80 ADORA2A (0.51) PDE10ATDP1DHODHKDM4EALDH1A1
SCHEMBL23946320 0.78 L3MBTL1 (0.40) PDE10ATDP1L3MBTL1KDM4EALDH1A1
SCHEMBL23946300 0.78 KDM4E (0.37) KCNH2PDE10ATDP1L3MBTL1KDM4E
SCHEMBL18235113 0.78 ADORA2A (0.49) PDE10ADHODHL3MBTL1KDM4EALDH1A1
SCHEMBL23946302 0.77 KDM4E (0.39) KCNH2PDE10ATDP1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES IDO1, IDO2, AZI2 KCNH2 8/4885PDE10A 704/4885TDP1 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.