Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.41 |
| ▸ | WHR1 | P49842 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23946244 | 0.97 | DHFR (0.50) | DHFRL3MBTL1GAAADORA1KDM4E | |
| SCHEMBL23946312 | 0.97 | DHFR (0.50) | DHFRL3MBTL1GAAADORA1KDM4E | |
| SCHEMBL23946318 | 0.97 | DHFR (0.50) | DHFRL3MBTL1GAAADORA1KDM4E | |
| SCHEMBL20233959 | 0.92 | ADORA2A (0.51) | GAAKDM4EALDH1A1DHODHADORA2A | |
| SCHEMBL23946342 | 0.89 | KDM4E (0.50) | L3MBTL1GAAKDM4EALDH1A1DHODH | |
| SCHEMBL23946337 | 0.88 | ADORA2A (0.43) | DHFRL3MBTL1GAAADORA1KDM4E | |
| SCHEMBL18874582 | 0.87 | ATM (0.56) | L3MBTL1KDM4EALDH1A1ADORA2ALMNA | |
| SCHEMBL18235113 | 0.87 | ADORA2A (0.49) | L3MBTL1GAAKDM4EALDH1A1DHODH | |
| SCHEMBL23946287 | 0.86 | DHFR (0.44) | DHFRL3MBTL1GAAADORA1KDM4E | |
| SCHEMBL23946249 | 0.86 | ADORA1 (0.43) | DHFRL3MBTL1ADORA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210328153-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210328153-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | IDO1, IDO2, AZI2 | DHFR 580/4885L3MBTL1 2765/4885GAA 3719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.