SCHEMBL23947761

SCHEMBL23947761

O=C(CCl)N1CCCN(C(=O)CN2CCc3sccc3C2c2cccc(F)c2)CC1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LHCGR P22888 4/20 0.50
HHAT Q5VTY9 4/20 0.39
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
GRIN2B Q13224 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23947745 0.86 LHCGR (0.48) LHCGRHHATNPSR1L3MBTL1
SCHEMBL29763691 0.80 HHAT (0.40) LHCGRHHAT
SCHEMBL23947759 0.80 HHAT (0.40) LHCGRHHAT
SCHEMBL2308598 0.70 LHCGR (0.52) LHCGRHHATL3MBTL1
SCHEMBL2303975 0.70 LHCGR (0.52) LHCGRHHATSMN1; SMN2
SCHEMBL2307398 0.70 LHCGR (0.52) LHCGRHHATSMN1; SMN2LMNA
SCHEMBL2311930 0.70 LHCGR (0.51) LHCGRHHATSMN1; SMN2
SCHEMBL2307742 0.70 LHCGR (0.51) LHCGRHHATLMNA
SCHEMBL23947746 0.69 HHAT (0.46) HHAT
SCHEMBL29763656 0.69 HHAT (0.46) HHAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12533339-B2 Small molecule antiviral drug treatment for human papillomavirus infections THE TRUSTEES OF INDIANA UNIVERSITY (US) 2026-01-27 US disclosed
US-20240173291-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2024-05-30 US disclosed
US-11877999-B2 Small molecule antiviral drug treatment for human papillomavirus infections THE TRUSTEES OF INDIANA UNIVERSITY (US) 2024-01-23 US disclosed
US-11628158-B2 Small molecule antiviral drug treatment for human papillomavirus infections THE TRUSTEES OF INDIANA UNIVERSITY (US) 2023-04-18 US disclosed
US-20230047626-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2023-02-16 US disclosed
US-20230047626-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2023-02-16 US disclosed
US-20220142973-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2022-05-12 US disclosed
US-20220142973-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2022-05-12 US disclosed
WO-2021212010-A2 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY (US) 2021-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047626-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS TP53, EIF2AK2, POLI LHCGR 3029/4885HHAT 2179/4885NPSR1 4713/4885
US-11877999-B2 Small molecule antiviral drug treatment for human papillomavirus infections TP53, EIF2AK2, POLI LHCGR 3029/4885HHAT 2179/4885NPSR1 4713/4885
US-20220142973-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS TP53, EIF2AK2, POLI LHCGR 3029/4885HHAT 2179/4885NPSR1 4713/4885
US-12533339-B2 Small molecule antiviral drug treatment for human papillomavirus infections CCND3, CCND1, TPD52L2 LHCGR 630/4885HHAT 2716/4885NPSR1 3458/4885
US-20240173291-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS TP53, EIF2AK2, POLI LHCGR 3029/4885HHAT 2179/4885NPSR1 4713/4885
US-11628158-B2 Small molecule antiviral drug treatment for human papillomavirus infections TP53, EIF2AK2, POLI LHCGR 3029/4885HHAT 2179/4885NPSR1 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.