⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21746672 | 0.71 | — | — | |
| SCHEMBL20994728 | 0.70 | — | — | |
| SCHEMBL21746668 | 0.69 | — | — | |
| SCHEMBL26863427 | 0.68 | — | — | |
| SCHEMBL23947882 | 0.68 | — | — | |
| SCHEMBL26863450 | 0.67 | — | — | |
| SCHEMBL23586638 | 0.67 | — | — | |
| SCHEMBL20243798 | 0.61 | — | — | |
| SCHEMBL21588743 | 0.60 | APLNR (0.32) | — | |
| SCHEMBL15689636 | 0.57 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211882-A1 | METHODS FOR PREPARING TYROSINE RECEPTOR KINASE INHIBITORS | PYRAMID BIOSCIENCES, INC. (US) | 2021-10-21 | — | — | WO | disclosed |