Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.77 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23947343 | 0.93 | PTPN22 (0.74) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947423 | 0.92 | PTPN22 (0.78) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947992 | 0.91 | PTPN22 (0.77) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947424 | 0.91 | PTPN22 (0.77) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947371 | 0.90 | PTPN22 (0.75) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947417 | 0.89 | PTPN22 (0.80) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23948060 | 0.88 | PTPN22 (0.79) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947991 | 0.88 | PTPN22 (0.68) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947584 | 0.88 | PTPN22 (0.72) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947391 | 0.87 | PTPN22 (1.00) | PTPN22PLAUPLAURHDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211191-A1 | NOVEL LYMPHOID-SPECIFIC TYROSINE PHOSPHATASE (LYP) INHIBITORS | PURDUE RESEARCH FOUNDATION (US) | 2021-10-21 | — | — | WO | disclosed |
| US-20210323926-A1 | Novel Lymphoid-Specific Tyrosine Phosphatase (LYP) Inhibitors | PURDUE RESEARCH FOUNDATION (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323926-A1 | Novel Lymphoid-Specific Tyrosine Phosphatase (LYP) Inhibitors | PTPN22, PTPN1, PTPRCAP | PTPN22 1/4885PLAU 4337/4885PLAUR 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.