Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.74 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP10 | P09238 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23947993 | 0.93 | PTPN22 (0.72) | PTPN22MMP2PLAUPLAURMMP12 | |
| SCHEMBL23947990 | 0.93 | PTPN22 (0.77) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23948060 | 0.90 | PTPN22 (0.79) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947423 | 0.90 | PTPN22 (0.78) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947424 | 0.89 | PTPN22 (0.77) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947992 | 0.89 | PTPN22 (0.77) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947564 | 0.89 | PTPN22 (0.71) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947952 | 0.89 | PTPN22 (0.66) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947371 | 0.88 | PTPN22 (0.75) | PTPN22PLAUPLAURHDAC8HDAC3 | |
| SCHEMBL23947417 | 0.88 | PTPN22 (0.80) | PTPN22PLAUPLAURHDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211191-A1 | NOVEL LYMPHOID-SPECIFIC TYROSINE PHOSPHATASE (LYP) INHIBITORS | PURDUE RESEARCH FOUNDATION (US) | 2021-10-21 | — | — | WO | disclosed |
| US-20210323926-A1 | Novel Lymphoid-Specific Tyrosine Phosphatase (LYP) Inhibitors | PURDUE RESEARCH FOUNDATION (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323926-A1 | Novel Lymphoid-Specific Tyrosine Phosphatase (LYP) Inhibitors | PTPN22, PTPN1, PTPRCAP | PTPN22 1/4885ADAMTS5 896/4885ADAMTS4 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.