SCHEMBL23948150

SCHEMBL23948150

Cc1cc(C(N)=O)c(F)cc1Nc1ncc2c(n1)n(C1CCC(CO)CC1)c(=O)n2C

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 20/20 0.55
KCNH2 Q12809 5/20 0.54
TTK P33981 4/20 0.54
CSF1R P07333 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23948529 0.91 PRKDC (0.66) PRKDCKCNH2TTKCSF1R
SCHEMBL23948499 0.90 PRKDC (0.64) PRKDCKCNH2TTKCSF1R
SCHEMBL29502098 0.90 PRKDC (0.64) PRKDCKCNH2TTKCSF1R
SCHEMBL23948470 0.90 PRKDC (0.63) PRKDCKCNH2TTKCSF1R
SCHEMBL29501924 0.90 PRKDC (0.48) PRKDCKCNH2TTKCSF1R
SCHEMBL25057359 0.90 PRKDC (0.48) PRKDCKCNH2TTKCSF1R
SCHEMBL23948153 0.90 PRKDC (0.53) PRKDCKCNH2TTKCSF1R
SCHEMBL23948244 0.89 PRKDC (0.68) PRKDCKCNH2TTKCSF1R
SCHEMBL29502018 0.89 PRKDC (0.68) PRKDCKCNH2TTKCSF1R
SCHEMBL23948136 0.89 PRKDC (0.63) PRKDCKCNH2TTKCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4137491-A1 IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) 2023-02-22 EP disclosed
WO-2021209055-A1 IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE 成都百裕制药股份有限公司 2021-10-21 WO disclosed