SCHEMBL29502018

SCHEMBL29502018

Cc1cc(C(N)=O)c(F)cc1Nc1ncc2c(n1)n(C1CCN(C)CC1)c(=O)n2C

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 20/20 0.68
KCNH2 Q12809 4/20 0.68
TTK P33981 3/20 0.54
CSF1R P07333 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23948244 1.00 PRKDC (0.68) PRKDCKCNH2TTKCSF1R
SCHEMBL23948470 0.92 PRKDC (0.63) PRKDCKCNH2TTKCSF1R
SCHEMBL23948529 0.92 PRKDC (0.66) PRKDCKCNH2TTKCSF1R
SCHEMBL23948499 0.91 PRKDC (0.64) PRKDCKCNH2TTKCSF1R
SCHEMBL29502098 0.91 PRKDC (0.64) PRKDCKCNH2TTKCSF1R
SCHEMBL23948211 0.91 PRKDC (0.69) PRKDCKCNH2TTKCSF1R
SCHEMBL29502026 0.90 PRKDC (0.64) PRKDCKCNH2TTKCSF1R
SCHEMBL23948504 0.90 PRKDC (0.64) PRKDCKCNH2TTKCSF1R
SCHEMBL23948136 0.89 PRKDC (0.63) PRKDCKCNH2TTKCSF1R
SCHEMBL23948150 0.89 PRKDC (0.55) PRKDCKCNH2TTKCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315834-B Imidazolone derivatives and their use in medicine 成都百裕制药股份有限公司 2024-01-05 CN disclosed
CN-114315834-A Imidazolidinone derivatives and their use in medicaments 成都百裕制药股份有限公司 2022-04-12 CN disclosed