Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26159709 | 1.00 | MERTK (0.44) | MERTKSYKMEN1KMT2AMAPK8 | |
| SCHEMBL25057374 | 0.90 | SYK (0.41) | MERTKSYKMEN1KMT2AMAPK8 | |
| SCHEMBL14656638 | 0.89 | MAPK8 (0.54) | MERTKSYKMAPK8MAPK9 | |
| SCHEMBL26931049 | 0.88 | MERTK (0.57) | MERTKSYKMAPK8MAPK9PPARG | |
| SCHEMBL26931042 | 0.88 | MERTK (0.57) | MERTKSYKMAPK8MAPK9PPARG | |
| SCHEMBL15249748 | 0.88 | SYK (0.51) | MERTKSYKMEN1KMT2APPARG | |
| SCHEMBL26161013 | 0.85 | SYK (0.49) | MERTKSYKMEN1KMT2AMAPK8 | |
| SCHEMBL1226594 | 0.85 | MEN1 (0.49) | MERTKSYKMEN1KMT2AMAPK8 | |
| SCHEMBL23948485 | 0.85 | SYK (0.38) | MERTKSYKMEN1KMT2APPARG | |
| SCHEMBL26159756 | 0.85 | SYK (0.38) | MERTKSYKMEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4137491-A1 | IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE | Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021209055-A1 | IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2021-10-21 | — | — | WO | disclosed |