Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26159727 | 1.00 | SYK (0.38) | SYKMEN1KMT2AMERTKPPARG | |
| SCHEMBL26159756 | 1.00 | SYK (0.38) | SYKMEN1KMT2AMERTKPPARG | |
| SCHEMBL23948231 | 0.85 | MERTK (0.44) | SYKMEN1KMT2AMERTKPPARG | |
| SCHEMBL25057374 | 0.85 | SYK (0.41) | SYKMEN1KMT2AMERTKPPARG | |
| SCHEMBL26159709 | 0.85 | MERTK (0.44) | SYKMEN1KMT2AMERTKPPARG | |
| SCHEMBL23948486 | 0.85 | ALDH1A1 (0.55) | SYKMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29502066 | 0.85 | ALDH1A1 (0.55) | SYKMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29501913 | 0.85 | ALDH1A1 (0.55) | SYKMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL25419189 | 0.85 | ALDH1A1 (0.55) | SYKMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL26159721 | 0.85 | ALDH1A1 (0.55) | SYKMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021209055-A1 | IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2021-10-21 | — | — | WO | disclosed |