Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 16/20 | 0.69 |
| ▸ | IMPDH1 | P20839 | 8/20 | 0.69 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14039597 | 0.90 | IMPDH2 (0.73) | IMPDH2IMPDH1AAK1ROCK2ROCK1 | |
| SCHEMBL2689376 | 0.88 | IMPDH2 (0.74) | IMPDH2IMPDH1AAK1ROCK2ROCK1 | |
| SCHEMBL12343257 | 0.88 | IMPDH2 (0.76) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL7214976 | 0.87 | IMPDH2 (0.74) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL12300716 | 0.84 | IMPDH2 (0.70) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL12828059 | 0.83 | IMPDH2 (0.69) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL12342886 | 0.83 | IMPDH2 (0.66) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL13917796 | 0.83 | IMPDH2 (0.71) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL12342857 | 0.83 | IMPDH2 (0.68) | IMPDH2IMPDH1AAK1ROCK2ROCK1 | |
| SCHEMBL12342889 | 0.82 | IMPDH2 (0.65) | IMPDH2IMPDH1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021209563-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY RESPIRATORY SYNDROME-RELATED CORONAVIRUS | SOM INNOVATION BIOTECH, S.A. (ES) | 2021-10-21 | — | — | WO | disclosed |