Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23949010 | 0.88 | PDE10A (0.35) | KDM4EATML3MBTL1ALDH1A1TSHR | |
| SCHEMBL23948403 | 0.87 | ADORA3 (0.35) | ADORA3ADORA2AKDM4EATML3MBTL1 | |
| SCHEMBL23948332 | 0.82 | KDM4E (0.37) | KDM4EATML3MBTL1ALDH1A1TSHR | |
| SCHEMBL23948220 | 0.78 | KDM4E (0.36) | KDM4EATML3MBTL1ALDH1A1TSHR | |
| SCHEMBL23948462 | 0.78 | KDM4E (0.38) | KDM4EATML3MBTL1ALDH1A1TSHR | |
| SCHEMBL24291314 | 0.78 | KDM4E (0.40) | KDM4EATML3MBTL1ALDH1A1TSHR | |
| SCHEMBL24291009 | 0.78 | KDM4E (0.40) | KDM4EATML3MBTL1ALDH1A1TSHR | |
| SCHEMBL21890168 | 0.76 | KDM4E (0.36) | KDM4EATML3MBTL1ALDH1A1TSHR | |
| SCHEMBL23948288 | 0.75 | KDM4E (0.41) | KDM4EATML3MBTL1ALDH1A1TSHR | |
| SCHEMBL24291747 | 0.75 | KDM4E (0.37) | KDM4EATML3MBTL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323963-A1 | Functional Materials Based on Stable Chemical Structure | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323963-A1 | Functional Materials Based on Stable Chemical Structure | TEAD4, TEAD2, TEAD1 | ADORA3 3381/4885ADORA2A 2212/4885KDM4E 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.