Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23948262 | 0.94 | KDM4E (0.37) | KDM4EATML3MBTL1AOC3CDK4 | |
| SCHEMBL23948632 | 0.89 | KDM4E (0.34) | KDM4EATML3MBTL1AOC3CDK4 | |
| SCHEMBL23948339 | 0.88 | MAOA (0.34) | KDM4EATML3MBTL1MAOAMAOB | |
| SCHEMBL23948706 | 0.88 | AOC3 (0.33) | KDM4EATML3MBTL1AOC3CDK4 | |
| SCHEMBL23948404 | 0.86 | AOC3 (0.33) | KDM4EATML3MBTL1AOC3MAOA | |
| SCHEMBL23948243 | 0.83 | KDM4E (0.34) | KDM4EATML3MBTL1CDK4CDK6 | |
| SCHEMBL23948308 | 0.82 | KDM4E (0.33) | KDM4EATML3MBTL1ALDH1A1RPS6KA5 | |
| SCHEMBL23949030 | 0.81 | KDM4E (0.36) | KDM4EATML3MBTL1AOC3CDK4 | |
| SCHEMBL21890201 | 0.81 | KDM4E (0.45) | KDM4EATML3MBTL1ALDH1A1CYP2D6 | |
| SCHEMBL23948240 | 0.79 | KDM4E (0.38) | KDM4EATML3MBTL1ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323963-A1 | Functional Materials Based on Stable Chemical Structure | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323963-A1 | Functional Materials Based on Stable Chemical Structure | TEAD4, TEAD2, TEAD1 | KDM4E 2817/4885ATM 2872/4885L3MBTL1 1154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.