Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23948420 | 0.85 | GABRP (0.36) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL23948644 | 0.84 | TOP2A (0.37) | CYP1A2CYP1A1KEAP1CYP1B1KDM4E | |
| SCHEMBL23948640 | 0.83 | KDM4E (0.44) | CYP1A2KDM4EMAPTLMNAPOLB | |
| SCHEMBL21890437 | 0.82 | KDM4E (0.47) | CYP1A2KDM4EMAPTLMNAPOLB | |
| SCHEMBL16067066 | 0.81 | CYP1A2 (0.46) | CYP1A2CYP1A1KEAP1CYP1B1GABRP | |
| SCHEMBL2741513 | 0.80 | GABRP (0.50) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31571478 | 0.80 | GABRP (0.50) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29383997 | 0.80 | GABRP (0.50) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL23948271 | 0.79 | GABRP (0.37) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL23948674 | 0.78 | KDM4E (0.36) | CYP1A2GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323963-A1 | Functional Materials Based on Stable Chemical Structure | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323963-A1 | Functional Materials Based on Stable Chemical Structure | TEAD4, TEAD2, TEAD1 | CYP1A2 674/4885CYP1A1 670/4885KEAP1 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.