Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 18/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 13/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25701662 | 0.91 | CD274 (0.46) | CD274PDCD1MRGPRX4 | |
| SCHEMBL22748209 | 0.91 | CD274 (0.48) | CD274PDCD1 | |
| SCHEMBL23949387 | 0.90 | CD274 (0.50) | CD274PDCD1MRGPRX4 | |
| SCHEMBL24613148 | 0.88 | CD274 (0.49) | CD274PDCD1MRGPRX4 | |
| SCHEMBL21199744 | 0.87 | CD274 (0.43) | CD274PDCD1MRGPRX4 | |
| SCHEMBL18757330 | 0.87 | CD274 (0.43) | CD274PDCD1MRGPRX4 | |
| SCHEMBL30406865 | 0.87 | CD274 (0.43) | CD274PDCD1MRGPRX4 | |
| SCHEMBL20539877 | 0.86 | CD274 (0.61) | CD274PDCD1MRGPRX4 | |
| SCHEMBL29724447 | 0.86 | CD274 (0.61) | CD274PDCD1MRGPRX4 | |
| SCHEMBL25235488 | 0.85 | CD274 (0.46) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323922-A1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323922-A1 | PD-1/PD-L1 INHIBITORS | CD274, PDCD1, PDCD1LG2 | CD274 1/4885PDCD1 2/4885MRGPRX4 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.