Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25234442 | 0.89 | CD274 (0.38) | CD274PDCD1 | |
| SCHEMBL22748209 | 0.87 | CD274 (0.48) | CD274PDCD1 | |
| SCHEMBL24613148 | 0.86 | CD274 (0.49) | CD274PDCD1 | |
| SCHEMBL23949387 | 0.86 | CD274 (0.50) | CD274PDCD1 | |
| SCHEMBL23948775 | 0.85 | CD274 (0.48) | CD274PDCD1 | |
| SCHEMBL30406909 | 0.84 | PDCD1 (0.35) | CD274PDCD1 | |
| SCHEMBL25234694 | 0.84 | PDCD1 (0.35) | CD274PDCD1 | |
| SCHEMBL25701662 | 0.83 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL20539877 | 0.80 | CD274 (0.61) | CD274PDCD1 | |
| SCHEMBL29724447 | 0.80 | CD274 (0.61) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250144253-A1 | 3-((3-([1,1'-BIPHENYL]-3-YLMETHOXY)PHENOXY)METHYL)BENZONITRILE DERIVATIVES AND THE USE THEREOF | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2025-05-08 | — | — | US | disclosed |
| EP-4444423-A1 | 3-((3-([1,1'-BIPHENYL]-3-YLMETHOXY)PHENOXY)METHYL)BENZONITRILE DERIVATIVES AND THE USE THEREOF | Helmholtz-Zentrum Dresden - Rossendorf e.V. (DE) | 2024-10-16 | — | — | EP | disclosed |
| CN-118715214-A | 3- ((3- ([ 1,1' -Biphenyl ] -3-ylmethoxy) -phenoxy) methyl) benzonitrile derivative and application thereof | 赫姆霍兹-森德拉姆德雷斯顿-罗森多夫研究中心 | 2024-09-27 | — | — | CN | disclosed |
| WO-2023104744-A1 | 3-((3-([1,1'-BIPHENYL]-3-YLMETHOXY)PHENOXY)METHYL)BENZONITRILE DERIVATIVES AND THE USE THEREOF | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2023-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250144253-A1 | 3-((3-([1,1'-BIPHENYL]-3-YLMETHOXY)PHENOXY)METHYL)BENZONITRILE DERIVATIVES AND THE USE THEREOF | CYP4B1, UGT2B7, UGT1A4 | CD274 4285/4885PDCD1 4435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.