Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20540210 | 1.00 | S1PR1 (0.42) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL19764959 | 0.88 | HTR1A (0.48) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL29625396 | 0.88 | HTR1A (0.48) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL29625425 | 0.87 | HTR1A (0.45) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL19764953 | 0.87 | HTR1A (0.45) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL19764894 | 0.87 | HTR1A (0.45) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL29625414 | 0.87 | HTR1A (0.45) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL10362833 | 0.87 | HTR1A (0.45) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL23961383 | 0.86 | NR3C2 (0.41) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL9277764 | 0.84 | POLL (0.41) | S1PR1S1PR2S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323922-A1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323922-A1 | PD-1/PD-L1 INHIBITORS | CD274, PDCD1, PDCD1LG2 | S1PR1 1861/4885S1PR2 2393/4885S1PR4 3782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.