Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 8/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 5/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25058663 | 0.89 | NSD2 (0.37) | NSD2EGLN2GRM5CYP19A1CYP11B1 | |
| SCHEMBL30257183 | 0.89 | NSD2 (0.37) | NSD2EGLN2GRM5CYP19A1CYP11B1 | |
| SCHEMBL30353072 | 0.88 | NSD2 (0.37) | NSD2GRM5CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25554342 | 0.88 | NSD2 (0.37) | NSD2GRM5CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30257092 | 0.88 | NSD2 (0.37) | NSD2GRM5CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25554407 | 0.88 | NSD2 (0.37) | NSD2GRM5CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30257104 | 0.87 | NSD2 (0.36) | NSD2GRM5CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL23949601 | 0.87 | NSD2 (0.39) | NSD2CYP19A1CYP11B1CYP11B2PRKDC | |
| SCHEMBL30353055 | 0.87 | NSD2 (0.39) | NSD2CYP19A1CYP11B1CYP11B2PRKDC | |
| SCHEMBL25555246 | 0.87 | NSD2 (0.36) | NSD2GRM5CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4137481-A1 | ARYL OR HETEROARYL DERIVATIVE | Teijin Pharma Limited (JP) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021210650-A1 | ARYL OR HETEROARYL DERIVATIVE | 帝人ファーマ株式会社 | 2021-10-21 | — | — | WO | disclosed |